This is intended as a brief overview of the NICE
guidance. Methylphenidate is recommended for use as part of a
comprehensive treatment programme for children with a diagnosis of
severe Attention Deficit/ Hyperactivity Disorder (ADHD).
Caution is required in the prescribing of
methylphenidate for children and young people with epilepsy,
psychotic disorders, or a history of drug or alcohol dependence.
Diagnosis should be based on a timely,
comprehensive assessment conducted by a child/adolescent
psychiatrist or a paediatrician with expertise in ADHD. It should
also involve children, parents and carers and the child’s school,
and take into account cultural factors in the environment.
Multidisciplinary assessment, which may include educational or
clinical psychologists and social workers, is advisable for children
who present with indications of significant co-morbidity.
Treatment with methylphenidate should only be
initiated by child and adolescent psychiatrists or paediatricians
with expertise in ADHD, but continued prescribing and monitoring may
be performed by general practitioners, under shared care
arrangements with specialists. Careful titration is required to
determine the optimal dose level and timing. The drug should be
discontinued if improvement of symptoms is not observed after
appropriate dose adjustment.
A comprehensive treatment programme should
involve advice and support to parents and teachers, and could, but
does not need to, include specific psychological treatment (such as
behavioural therapy). While this wider service is desirable, any
shortfall in its provision should not be used as a reason for
delaying the appropriate use of medication.
Children on methylphenidate therapy should
receive regular monitoring. When improvement has occurred and the
child’s condition is stable, treatment can be discontinued at
intervals, under careful specialist supervision, in order to assess
both the child's progress and the need for continuation of therapy.
The remainder of the document has details on
clinical need, technology, evidence, implications for the NHS,
further research, implementation, clinical audit advice and a review
of the guidance together with information for patients
The Full document and a summary of evidence will
be available on the NICE website at
http://www.nice.org.uk/nice-web/Cat.asp?c=11652