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The Quince ...

Issue 44. 
 

Report suggests that a fifth of suicides are preventable
Obesity drug endorsed by NICE
Poll shows public still has trust in doctors

Compliance with unpleasant therapies

Report suggests that a fifth of suicides are preventable

The health service is being called on to step up efforts to protect people with mental health problems from harming themselves or other people after a report published this week showed that more than a fifth of suicides among people with mental illness could have been prevented.

About a quarter of the United Kingdom’s 6500 suicides each year occur among people with mental illness, some 12% of them while in hospital.

The National Confidential Inquiry into Suicide and Homicide by People with Mental Illness showed that many people at risk of suicide are simply slipping through the net. A quarter of those who committed suicide died within three months of being discharged from hospital, nearly half of them never making it to their first follow up appointment.

The report showed that nearly 50% of the suicides in England and Wales were among people being supervised under the enhanced “care programme approach”, which requires input from a multidisciplinary team of mental health specialists. But half of them were not taking their medication when they died or had missed their last appointment with community services.

Professor Louis Appleby, director of the inquiry, said that these latest figures from 1999 suggest that the fall in the suicide rate among the general population, which has been observed since the beginning of the 1990s, is continuing. However, suicides among people with mental illness have remained static.

Mental illness also contributes to about a third of the 600 murders that occur in the UK each year. Less than 10% of those accused of homicide in England and Wales, however, had been in contact with mental health services in the previous year.

Safety First. Five Year Report of the National Confidential Inquiry into Suicide and Homicide by People with Mental Illness can be accessed at the Department of Health’s website

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Obesity drug endorsed by NICE

The anti-obesity drug orlistat (Xenical) should be available throughout England and Wales on the NHS, the government’s drug advisory body has recommended. The decision by the National Institute for Clinical Excellence (NICE) should put an end to “postcode prescribing”, which has led to a 16-fold difference between the areas where it is most commonly prescribed and the areas where it is least prescribed.

The institute sets out strict guidelines for prescribing orlistat as one part of the management of obesity. It should be prescribed only to adults (aged 18 to 75 years) who either have a body mass index of ³28 (weight(kg)/(height(m)2)) and also have a serious illness (such as type 2 diabetes or hypertension) or have a body mass index of ³30 but have no associated illnesses. Before the drug is prescribed, a patient should have already 

lost at least 2.5kg by dieting and increasing physical activity.

To continue taking the drug, patients must also fulfil strict criteria. Treatment should continue for more than three months only if the patient has lost at least 5% of his or her body weight from the start of drug treatment; it should continue for more than six months only if weight loss has been at least 10% of body weight.

The recommendation will have a significant impact on the NHS drug budget. The cost of treatment per patient is estimated to be £537 ($806) a year. The institute estimates that if the guidance is implemented it will cost around £12m in the first year-double the current drug costs. This estimate is based on an extra 11000 people being prescribed orlistat.

Trials have shown that mean weight loss per year achieved with orlistat is 2.5 kg greater than that achieved with placebo. This has been accompanied by small but significant reductions in total cholesterol levels, the ratio of total cholesterol level to high density lipoprotein level and diastolic and systolic blood pressure. There is no evidence of the drug’s efficacy in reducing a person’s weight for periods over 12 months, and the drug is licensed for use only up to 24 months.

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Poll shows public still has trust in doctors

Trust in doctors does not seem to have been dented by the recent poor publicity that they have received over the Bristol surgery inquiry and the reports about the retention of body parts at Alder Hey Hospital, Liverpool.

A poll by the independent research agency MORI of almost 2000 adults, commissioned by the BMA, shows that the public trusts doctors to tell the truth more than any other group, including teachers, judges, and clergymen. Eighty nine per cent of the respondents thought that doctors told the truth, compared with 86% for teachers, 78% for judges and clergymen, 18% for journalists, and 17% for politicians.

Similarly, satisfaction with doctors remains high. The same proportion of the public (89%) said they were either very satisfied (36%) or fairly satisfied (53%) with the way doctors did their jobs. Only nurses scored more highly, with 95% of respondents saying that they were either very satisfied (54%) or fairly satisfied (41%). Dentists and teachers came third and fourth, with 84% and 82% respectively expressing satisfaction.

The scores compare well with last year’s poll. Trust in doctors has risen by two percentage points, though the proportion of those saying they are very satisfied has fallen by five percentage points.

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Compliance with unpleasant therapies

Chemotherapy given at home was compared with outpatient treatment in terms of colorectal cancer patients’ safety, compliance, use of health services, quality of life, and satisfaction with treatment. 87 patients receiving adjuvant or palliative chemotherapy for colorectal cancer were treated with fluorouracil (with or without folinic acid or levamisole) at outpatient clinic or at home.

Treatment related toxicity was similar in the two groups, but there were more voluntary withdrawals from treatment in the outpatient group than in the home group (14% v 2%, difference 12% (1% to 24%)). There were no differences between groups in terms of quality of life scores during and after treatment. Levels of patients’ satisfaction were higher in the home treatment group, specifically with regard to information received and nursing care. There were no significant differences in use of health services.

Home chemotherapy seemed an acceptable and safe alternative to hospital treatment for patients with colorectal cancer that may improve compliance and satisfaction with treatment.

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Last updated:

Copyright 2003 | Norman Vetter


Send mail to njvetter@hotmail.com with questions or comments